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Cancer immunotherapy, also known as monoclonal antibody therapy (mAb) and adoptive cell transfer (ACT) therapy for immune cells, is a way of treating cancer by regulating an immune response. In a range of tumor types, mAb treatment, which is based on promoting T cell function by inhibiting or activating immunoregulatory pathways, has produced notable therapeutic responses. Nevertheless, not all patients are able to sustain a robust immunological response after therapy. Finding predictive biomarkers is crucial in order to choose patients who will benefit from the therapy. To investigate immunological and tumor-immune interactions at the single-cell level, a new approach is needed due to the complexity of the tumor microenvironment and the dynamic nature of the immune response. Protein is normally produced or released in numerous, brief pulses, and in low quantities. Protein is an important chemical involved in a variety of physiological functions in cells. Because there are no effective PCR-like amplification methods for single-cell proteomics, a variety of analytical methods are used to assess a variety of critical factors, such as immunological diversity, intratumoral heterogeneity, and intercellular communication. For more: single cell proteomics?

Cancer immunotherapy, also known as monoclonal antibody therapy (mAb) and adoptive cell transfer (ACT) therapy for immune cells, is a way of treating cancer by regulating an immune response. In a range of tumor types, mAb treatment, which is based on promoting T cell function by inhibiting or activating immunoregulatory pathways, has produced notable therapeutic responses. Nevertheless, not all patients are able to sustain a robust immunological response after therapy. Finding predictive...

Deep Nature is a forum for the celebration of science and scientific ideas. We are open to all kinds of science--mainstream science, fringe science, rebel science, social science, spiritual science. This is the place for intellectual fellowship, scientific education and spirited debates. We put a premium on the diversity of ideas, fairness, mutual respect, civility, reason and curiosity. When you come, we ask that you bring both your passion and your consideration for others. Our goal is to build a genuine community of critical thinkers and socially-engaged lovers of science.

Deep Nature is a forum for the celebration of science and scientific ideas. We are open to all kinds of science--mainstream science, fringe science, rebel science, social science, spiritual science. This is the place for intellectual fellowship, scientific education and spirited debates. We put a premium on the diversity of ideas, fairness, mutual respect, civility, reason and curiosity. When you come, we ask that you bring both your passion and your consideration for others. Our goal is to...